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Melanocytes were then separated out to a cellular suspension that was expanded in culture.The area to be treated was then denuded with a dermabrader and the melanocytes graft applied.Segmental vitiligo (SV) differs in appearance, cause, and frequency of associated illnesses. It tends to affect areas of skin that are associated with dorsal roots from the spinal cord and is most often unilateral.

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Because of the high doses of UVA and psoralen, PUVA may cause side effects such as sunburn-type reactions or skin freckling.

With respect to improved repigmentation: topical corticosteroids are better than psoralen with sunlight, hydrocortisone plus laser light is better than laser light alone, gingko balboa is better than placebo, and oral minipulse of prednisolone (OMP) plus NB-UVB is better than OMP alone.

In cases of extensive vitiligo the option to de-pigment the unaffected skin with topical drugs like monobenzone, mequinol, or hydroquinone may be considered to render the skin an even colour.

The removal of all the skin pigment with monobenzone is permanent and vigorous.

The exposure time is managed so that the skin does not suffer overexposure.

Treatment can take a few weeks if the spots are on the neck and face and if they existed not more than 3 years.A serious potential side effect involves the risk of developing skin cancer, the same risk as an over-exposure to natural sunlight.Ultraviolet light (UVA) treatments are normally carried out in a hospital clinic.Between 70 and 85 percent of patients experienced nearly complete repigmentation of their skin.The longevity of the repigmentation differed from person to person.The name "vitiligo" was first used by the Roman physician Aulus Cornelius Celsus in his classic medical text De Medicina.

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