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These studies variably studied the effect of cinnamon on glycosylated haemoglobin, fasting plasma glucose, total cholesterol, LDL cholesterol and triglycerides []. The duration of these interventions ranged from 40 days to 4 months, the patient numbers varied from 25–109 in each trial and the amount of cinnamon administered per day varied from 1 to 6 g.Of these studies, 2 showed no significant reduction in glycaemia []. in 2003 studied a total of 60 patients, who were randomized to receive 1, 3, or 6 g of cinnamon daily or a placebo. Top Header Bar .customer-links #Custom Top Log Links a .

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Ceylon cinnamon is the most potent inhibitor of pancreatic amylase and intestinal sucrase [].

Cinnamon also possesses the ability to increase glycogen synthesis and inhibit gluconeogenesis, by increasing the activity of Pyruvate Kinase (PK) and decreasing that of Phoshoenol pyruvate carboxy kinase (PEPCK) [ To date several Randomized Controlled Studies exist that studied the effect of Cinnamon in type 2 adult diabetics.

Short durations of study and small number of subjects studied is universal.

Crepe ginger has not been studied adequately in humans to draw conclusions.

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During the last few years, even in the absence of good supporting evidence, the United States alone has recorded an increase of 380% in the use of herbal remedies [].

India, a country that is steeped in tradition and boasting a rich history of healing practices records a very high use of 67% among its diabetic population.

The majority of these patients (97%) used naturoapathy, which often included herbalism [].

This article will attempt to bridge the evidence for cellular mechanisms of action, and human studies for using some common CAMS such as Cinnamon and fenugreek and also attempt explore anti-diabetic properties of 2 herbs and the vegetable bitter gourd.

At present Cinnamon is sold as both a preventative and therapeutic supplement for many ailments including, metabolic syndrome, insulin resistance, T2 diabetes, hyperlipidaemia and arthritis [ A multitude of in-vitro studies have demonstrated that cinnamon increases glucose entry into cells by enhanced insulin receptor phosphorylation and translocation of the glucose transporter GLUT4 to the plasma membrane [].

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