Seroquel too sedating for bipolar dating vegaphone banjo
As with other antipsychotics, Seroquel should be used with caution in the elderly, especially during the initial dosing period.
The rate of dose titration may need to be slower, and the daily therapeutic dose lower, than that used in younger patients, depending on the clinical response and tolerability of the individual patient.
It must therefore be ensured that patients receive clear information on the appropriate dosage for their condition. For the treatment of schizophrenia For the treatment of schizophrenia, Seroquel should be administered twice a day.
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Long-term implications for cognitive and behavioural development are not known.
In placebo-controlled clinical trials with children and adolescent patients, quetiapine was associated with an increased incidence of extrapyramidal symptoms (EPS) compared to placebo in patients treated for schizophrenia, bipolar mania and bipolar depression (see section 4.8).
Changes in thyroid function tests have also been observed in children and adolescents.
Furthermore, the long-term safety implications of treatment with quetiapine on growth and maturation have not been studied beyond 26 weeks.
Seroquel is not recommended for use in children and adolescents below 18 years of age, due to a lack of data to support use in this age group.
The available evidence from placebo-controlled clinical trials is presented in sections 4.4, 4.8, 5.1 and 5.2.
Depending on the clinical response and tolerability of the individual patient, the dose may be adjusted within the range 150 to 750 mg/day.
For the treatment of moderate to severe manic episodes in bipolar disorder For the treatment of manic episodes associated with bipolar disorder, Seroquel should be administered twice a day.
Hypersensitivity to the active substance or to any of the excipients of this product.
Concomitant administration of cytochrome P450 3A4 inhibitors, such as HIV-protease inhibitors, azole-antifungal agents, erythromycin, clarithromycin and nefazodone, is contraindicated (see section 4.5).
The mean plasma clearance of quetiapine was reduced by 30 - 50% in elderly subjects when compared to younger patients.Tags: Adult Dating, affair dating, sex dating